Chih-Cheng Hsu, M.D., Dr.P.H.,
Institute of Population Health Sciences
EDUCATIONDr.P.H., School of Public Health and Tropical Medicine, Tulane University, USA
M.P.H., College of Public Health, National Taiwan University, Taiwan
M.D., School of Medicine, National Yang-Ming University, Taiwan
PROFESSIONAL EXPERIENCES- Director, Division of Geriatrics and Gerontology, Institute of Population Health Sciences, National Health Research Institutes, Taiwan (2012 - present)
- Associate Investigator, Center for Health Policy Research and Development, National Health Research Institutes, Taiwan (2006 - present)
- Assistant Investigator, Division of Health Policy Research, National Health Research Institutes, Taiwan (2001 - 2006)
RESEARCH INTERESTSDr. Hsu's research interests include tobacco control, quality assurance of diabetic care, epidemiology and prevention of chronic kidney diseases. His research team has made efforts to delineate effects of market opening on the longitudinal trend in smoking rates, to evaluate quality of diabetic care in primary care settings and to assess prevalence and awareness rate of chronic kidney diseases in Taiwan.
RESEARCH ACTIVITIES & ACCOMPLISHMENTSDr. Hsu has disclosed that high prevalence and low awareness of chronic kidney diseases might be one of important reasons contributing to high dialysis incidence in Taiwan. He also initiated a multi-center intervention study for diabetic care 4 years ago and concluded that intensive case management can significantly benefit glucose control for type 2 diabetic patients, which is the first randomized control study for diabetic intervention in primary care setting in Taiwan.
SELECTED PUBLICATIONSPublication list (since 2010)
1.Wu IC, Lin CC, Hsiung CA, Wang CY, Wu CH, Chan DCD, Li TC, Lin WY, Huang KC, Chen CY, Hsu CC. Epidemiology of Sarcopenia among Community-Dwelling Older Adults in Taiwan: A Pooled Analysis for a Broader Adoption of Sarcopenia Assessments. Geriatrics & Gerontology International. 2014 Feb; 14 (Suppl 1): 52-60.
2.Hsu TW, Liu JS, Hung SC, Kuo KL, Chang YK, Chen YC, Hsu CC, Tarng DC. Renoprotective Effect of Renin-Angiotensin System Blockade among Advanced Chronic Kidney Disease Non-dialyzed Patients with Hypertension and Anemia. JAMA Internal Medicine. 2013. (Article in Press).
3.Tai TS, Hsu CC, Pai HC, Liu WH, Hsu YH. The Association between Hyperuricemia and Betel Nut Chewing in Taiwanese Men: a cross-sectional study. BMC Public Health. 2013 Dec 5; 13: 1136.
4.Kuo JZ, Sheu WH, Assimes TL, Hung YJ, Absher D, Chiu YF, Mak J, Wang JS, Kwon S, Hsu CC, Goodarzi MO, Lee IT, Knowles JW, Miller BE, Lee WJ, Juang JM, Wang TD, Guo X, Taylor KD, Chuang LM, Hsiung CA, Quertermous T, Rotter JI, Chen YD. Trans-ethnic fine mapping identifies a novel independent locus at the 3' end of CDKAL1 and novel variants of several susceptibility loci for type 2 diabetes in a Han Chinese population. Diabetologia. 2013 Dec; 56(12): 2619-28.
5.Hsu YH, Pai HC, Chang YM, Liu WH, Hsu CC. Alcohol consumption is inversely associated with stage 3 chronic kidney disease in middle-aged Taiwanese men. BMC Nephrol. 2013 Nov 17; 14(1): 254.
6.Wu IC, Chang HY, Hsu CC, Chiu YF, Yu SH, Tsai YF, Shen SC, Kuo KN, Chen CY, Liu K, Lee MM, Hsiung CA. Association Between Dietary Fiber Intake and Physical Performance in Older Adults: A Nationwide Study in Taiwan. PLoS One 2013 Nov 11; 8(11)
7.Hsu YH, Huang MC, Chang HY, Shin SJ, Wahlqvist ML, Chang YL, Hsu KC, Hsu CC. Association between serum ferritin and microalbuminuria in Type 2 diabetes in Taiwan. Diabetic Medicine. 2013 Nov; 30(11): 1367-1373.
8.Wen CP, Tsai MK, Hsu CC. Cessation guideline: to develop or not to develop? A question for each developing country. Addiction, 2013 Aug; 108(8): 1485-6.
9.Chang YT, Wu JL, Hsu CC, Wang JD, Sung JM. Diabetes and end-stage renal disease synergistically contribute to increased incidence of cardiovascular events: A nation-wide follow-up study during 1998-2009. Diabetes Care. 2013 Aug 6.
10.Chang CI, Chen CY, Huang KC, Wu CH, Hsiung C, Hsu CC, Chen CY. Comparison of three BIA muscle indices for sarcopenia screening in old adults. European Geriatric Medicine. 2013 Jun; 4(3): 145-149.
11.Lin YL, Yen YY, Chen HS, Liu YC, Chang CS, Chen CM, Chen FL, Hsu CC, Lee CH, Hu CY, Huang HL. Child dental fear in low-income and non-low-income families: A school-based survey study. Journal of Dental Sciences. 2013 May. (Article in Press).
12.Kao TW, Chang YY, Chen PC, Hsu CC, Chang YK, Chang YH, Lee LJ, Wu KD, Tsai TJ, Wang JD. Lifetime costs for peritoneal dialysis and hemodialysis in patients in Taiwan. Perit Dial Int. 2013 May 1. (Article in Press).
13.Liu WH, Hsu CC, Hsu YH. Chewing areca nut as an independent risk factor for proteinuria in middle-aged men. Kaohsiung J Med Sci. 2013 Apr; 29(4): 214-20.
14.Hsu CC, Jhang HR, Chang WT, Lin CH, Shin SJ, Hwang SJ, Huang MC. Associations between dietary patterns and kidney function indicators in type 2 diabetes. Clinical Nutrition. 2013 Apr 15. (Article in Press).
15. Chang CI, Li CM, Chen CY, Lin LJ, Huang KC, Hsu CC, Lin CC, Chen CY. A pilot study of Frailty screening and Case Management in the Taipei Elderly Annual Health Examination. Bulletin of Taipei Medical Association. 2013; 57(2): 14-17.
16.Li CL, Chang HY, Hsu CC, Lu JF, Fang HL. Joint predictability of health related quality of life and leisure time physical activity on mortality risk in people with diabetes. BMC Public Health. 2013 Jan 24; 13: 67.
17.Chen JH, Pan WH, Hsu CC, Yeh WT, Chuang SY, Chen PY, Chen HC, Chang CT, Huang WL. Impact of obesity and hypertriglyceridemia on gout development with or without hyperuricemia: a prospective study. Arthritis Care Res (Hoboken). 2013 Jan; 65(1): 133-40.
18.Lee LC, Yen YY, Lin PL, Lin YC, Hu CY, Lin YY, Chen FL, Hsu CC, Peng WD, Huang HL. Tobacco Knowledge and Attitude toward Tobacco Policy Associated with Smoking Behavior among Guardians of Elementary School Student in Kaohsiung City. The Taiwan Journal of Oral Medical Sciences. 2013; 28(1): 24-45. (written in Chinese with an English abstract)
19.Hsu CC, Chang HY, Huang MC, Hwang SJ, Yang YC, Lee YS, Shin SJ, Tai TY. HbA1c variability is associated with microalbuminuria development in type 2 diabetes: a 7-year prospective cohort study. Diabetologia. 2012 Dec; 55(12): 3163-3172.
20.Chiu YW, Weng YH, Lo HL, Shih YH, Hsu CC, Kuo KN. Comparison of accessing online databases between physicians and nurses in Taiwan. Informatics for Health and Social Care. 2012. Dec; 37(4): 230-41.
21.Wahlqvist ML, Lee MS, Chuang SY, Hsu CC, Tsai HN, Yu SH, Chang HY. Increased Risk of Affective Disorders in Type 2 Diabetes Is Minimised by Sulfonylurea and Metformin Combination: A Population-Based Cohort Study. BMC Medicine. 2012; Nov 29; 10(1): 150.
22.Weng YH, Hsu CC, Shih YH, Lo HL, Chiu YW, Kuo, KN. Dissemination of systematic reviews in a hospital setting: a comparative survey for spreading use of the Cochrane Library. Postgraduate Medical Journal. 2012 Sep; 88(1043): 511-514.
23.Wang WS, Wahlqvist ML, Hsu CC, Chang HY, Chang WC, Chen CC. Age- and gender-specific population attributable risks of metabolic disorders on all-cause and cardiovascular mortality in Taiwan. BMC Public Health. 2012 Feb 10; 12(1): 111.
24.Huang HL, Yen YY, Lin PL, Chiu CH, Hsu CC, Chen T, Hu CY, Lin YY, Lee CH, Chen FL. Household secondhand smoke exposure of elementary schoolchildren in Southern Taiwan and factors associated with their confidence in avoiding exposure: a cross-sectional study. BMC Public Health. 2012 Jan 17; 12: 40.
25.Yang DC, Lee LJ, Hsu CC, Chang YY, Wang MC, Lin WH, Chang CM, Wang JD. Estimation of Expected Life-Years Saved From Successful Prevention of End-Stage Renal Disease in Elderly Patients With Diabetes: A nationwide study from Taiwan. Diabetes Care. 2012; 35: 2279-2285.
26.Hsu CC, Lee CH, Wahlqvist ML, Huang HL, Chang HY, Chen L, Shih SF, Shin SJ, Tsai WC, Chen T, Huang CT, Cheng JS. Poverty increases type 2 diabetes incidence and inequality of care despite universal health coverage. Diabetes Care. 2012; 35: 2286-2292.
27.Yu FJ, Huang MC, Chang WT, Chung HF, Wu CY, Shin SJ, Hsu CC. Increased Ferritin Concentrations Correlate with Insulin Resistance in Female Type 2 Diabetic Patients. Annals of Nutrition and Metabolism. 2012; 61: 32-40.
28.Wahlqvist ML, Lee MS, Hsu CC, Chuang SY, Lee JT, Tsai HN. Metformin-inclusive sulfonylurea therapy reduces the risk of Parkinson's disease occurring with Type 2 diabetes in a Taiwanese population cohort. Parkinsonism and Related Disorders. 2012; 18: 753-758.
29.Huang HL, Hsu CC, Peng WD, Yen YY, Chen T, Hu CY, Shi HY, Lee CH, Chen FL, Lin PL. Analysis of Influential Factors Associated with the Smoking Behavior of Aboriginal Schoolchildren in Remote Taiwanese Mountainous Areas. Journal of School Health 2012; 82: 318-327.
30.Chang WC, Wahlqvist ML, Chang HY, Hsu CC, Lee MS, Wang WS, and Hsiung CA. A bean-free diet increases the risk of all-cause mortality among Taiwanese women: the role of the metabolic syndrome. Public Health Nutrition. 2011; 15(4): 663-72.
31.Chang YK, Hsu CC, Hwang SJ, Chen PC, Huang CC, Li TC, Sung FC. A Comparative Assessment on Survival between Propensity Score Matched Patients with Peritoneal Dialysis and Hemodialysis in Taiwan. Medicine. 2012; 91(3): 144-151.
32.Hsu YH, Liu WH, Chen W, Kuo YC, Hsiao CY, Hung PH, Jong IC, Chiang PC, Hsu CC. Association of betel nut chewing with chronic kidney disease : A retrospective 7-year study in Taiwan. Nephrology. 2011; 16 : 751-757
33.Hsu CC, Chang HY, Huang MC, Hwang SJ, Yang YC, Tai TY, Yang HJ, Chang CT, Chang CJ, Li YS, Shin SJ, Kuo KN. Association between Insulin Resistance and Development of Microalbuminuria in Type 2 Diabetes: A Prospective Cohort Study. Diabetes Care. 2011; 34: 982-987.
34.Lee MS, Hsu CC, Wahlqvist ML, Tsai HN, Chang YH, Huang YC. Type 2 diabetes increases and metformin reduces total, colorectal, liver and pancreatic cancer incidences in Taiwanese: a representative population prospective cohort study of 800,000 individuals. BMC Cancer. 2011; 11: 20.
35.Wen CP, Chan HT, Tsai MK, Cheng TYD, Chung WSI, Chang YC, Hsu HL, Tsai SP, Tsao CK, Wai JPM, Hsu CC. Attributable mortality burden of metabolic syndrome: comparison with its individual components. European Journal of Cardiovascular Prevention & Rehabilitation. 2011; 18 (4): 561-573.
36.Hsu CC, Wahlqvist ML, Lee MS, Tsai HN. Incidence of dementia is increased in type 2 diabetes and reduced by the use of sulfonylureas and metformin: a national representative cohort study in Taiwan. Journal of Alzheimer's Disease. 2011; 24(3): 485-493.
37.Hsu CC, Lee CH, Hwang SJ, Huang SW, Yang WC, Chang YK, Tsai DFC, Kuo KN. Outcomes of overseas kidney transplantation in chronic haemodialysis patients in Taiwan. Nephrology. 2011;16 (3): 341-348.
38.Shih YH, Lo HL, Weng YH,Ting HW, Hsu CC, Chen C, Chiu YW, Kuo KN. Adoption of Evidence-Based Medicine: A National Survey of Regional Hospital Physicians. Journal of Medical Education. 2010; 14: 163-172. (written in Chinese with an English abstract)
39.Chang HY, Hsu CC, Pan WH, Liu WN, Cheng JYC, Tseng CH, Bai CH, Yeh WT, Hurng BS. Gender differences in trends in diabetes prevalence from 1993 to 2008 in Taiwan. Diabetes Research and Clinical Practice. 2010; 90: 358-364.
40.Chen KC, Yen YY, Tsai WL, Huang CM, Hsu CC, Lin YY, Huang HL. Area Comparison of Cigarette Smoking: Knowledge, Attitude, and Behavior among Guardian of the Primary School Students in Pin-Tung County. The Taiwan Journal of Oral Medical Sciences. 2010; 26(1): 04-20. (written in Chinese with an English abstract)
41.Lu YY, Yen YY, Tsai WL, Huang CM, Hsu CC, Lin YY, Huang HL. Life Stress, Deviant Behaviors, and Parenting Style Associated with Children's Cigarette Smoking, Alcohol Drinking and Betel Quid Chewing in Elementary Schools. The Taiwan Journal of Oral Medical Sciences. 2010; 26(1): 21-40. (written in Chinese with an English abstract)
42.Chen N, Hsu CC, Yamagata K, Langham R. Challenging the Chronic Kidney Disease: Experience from Chronic Kidney Disease Prevention Programs in Shanghai, Japan, Taiwan and Australia. Nephrology. 2010; 15 (Suppl 2): 31-36.
43.Chiu YW, Weng YH, Lo HL, Shih YH, Hsu CC, Kuo NK. Impact of a nationwide outreach program on the diffusion of evidence-based practice in Taiwan. International Journal for Quality in Health Care. 2010; 22(5): 430-436.
44.Wahlqvist ML, Chang HY, Chen CC, Hsu CC, Chang WC, Wang WS, Hsiung CA. Is impaired energy regulation the core of the metabolic syndrome in various ethnic groups of the USA and Taiwan? BMC Endocrine Disorders. 2010; 10: 11.
45.Chiu YW, Weng YH, Lo HL, Hsu CC, Shih YH, Kuo KN. Comparison of evidence-based practice between physicians and nurses: A national survey of regional hospitals in Taiwan. Journal of Continuing Education in the Health Professions. 2010; 30(2): 132-138.
46.Li CL, Lin NY, Wang HH, Hsu CC, Hurng BS, Chang HY. A population study on changes in diabetes self-care behaviors in Taiwan between 2001 and 2005. Preventive Medicine. 2010; 50: 308-309.
47.Huang CM, Yen YY, Chen FL, Hsu CC, Lee CH, Lin YY, Huang HL. School-level Policy for Tobacco Control and Individual-level Characteristics in Relation to Cigarette Smoking among Children¡GA Multilevel Study of Pintung County. Taiwan Journal of Public Health. 2010; 29(2): 145-157. (written in Chinese with an English abstract)
48.Huang HL, Chen FL, Hsu CC, Yen YY, Chen T, Huang CM, Shi HI, Hu CY and Lee CH. A Multilevel-Based Study of School Policy for Tobacco Control in Relation to Cigarette Smoking among Children in Elementary Schools: Gender Differences. Health Education Research. 2010; 25(3): 451-463.
49.Hsu CC, Hwang SJ, Tai TY, Chen T, Huang MC, Shin SJ, Wen CP, Shih YT, Yang HJ, Chang CT, Chang CJ, Loh CH, Fuh MT, Li YS, Chang HY. Cigarette Smoking and Proteinuria in Taiwanese Men with Type 2 Diabetes Mellitus. Diabtic Medicine. 2010; 27: 295-302.
50.Huang MC, Hsu CC, Wang HS, Shin SJ. A prospective randomized controlled trial to evaluate effectiveness of registered dietitian led diabetes management on glycemic and diet control in a primary care setting in Taiwan. Diabtes Care. 2010; 33 (2): 233-239.