Dong-Ming Huang, Ph.D.
Center for Nanomedicine Research
EDUCATIONPh.D., Department of Pharmacology, College of Medicine, National Twain University (2002)
M.S., Graduate Institute of Basic Medical Science, Chang-Gung University (1996)
B.S., Department of Medical Technology, Taipei Medical University (1994)
PROFESSIONAL EXPERIENCESAssistant Investigator, Center for Nanomedicine Research, National Health Research Institutes (2006-present)
Postdoctoral Fellow, Stem Cell Research Center, National Health Research Institutes (2004-2006)
Postdoctoral Fellow, Department of Pharmacology, College of Medicine, National Twain University (2002-2004)
RESEARCH INTERESTSDr. Huang's research interests focus on the development of novel nanodevice or nanotechnology for medical applications. His laboratory and his collaborators are developing novel nanoparticles for stem cell tracking, overcoming multidrug resistance (MDR) of cancer and gene delivery. Huang also studies nanoparticle-derived signal transduction for evaluating the biosafety of nanoparticle as a stem cell tracker.
RESEARCH ACTIVITIES & ACCOMPLISHMENTSDr. Huang was initially devoted to the study of developing anticancer drugs. In 2004, Dr. Huang shifted to a new subject about the combination of nanotechnology and stem cell biology. In 2006, Dr. Huang joined Center for Nanomedicine Research. At the meantime, Dr. Huang endeavors to coordinate nanotechnology and tumor therapy for overcoming multidrug resistance (MDR). With great enterprise, he has published peer-reviewed papers in international journals with high impact factor.
SELECTED PUBLICATIONS1. Liu HM, Wu SH, Lu CW, Yao M, Hsiao JK, Hung Y, Lin YS, Mou CY, Yang CS, Huang DM*, Chen YC. Mesoporous Silica Nanoparticles Improve Magnetic Labelling Efficiency in Human Stem Cells. Small, In Press. (*=Corresponding Author)
2. Tsai CP, Hung Y, Chou YH, Yao M, Huang DM, Hsiao JK, Chang C, Cheng YC, Mou CY. High Contrast Paramagnetic Fluorescent Mesoporous Silica Nanorod as a Multifunctional Cell-imaging Probe. Small, In Press.
3. Chung TH, Wu SH, Yao M, Lu CW, Lin YS, Hung Y, Mou CY, Chen YC, Huang DM*. The effect of surface charge on the uptake and biological function of mesoporous silica nanoparticles in 3T3-L1 cells and human mesenchymal stem cells. Biomaterials, 28:2959-2966, 2007. (*=Corresponding Author)
4. Lu CW, Hung Y, Hsiao JK, Ming Yao, Chung TH, Lin YS, Wu SH, Hsu SC, Liu HM, Mou CY, Yang CS, Huang DM*, Chen YC. Bifunctional Magnetic Silica Nanoparticles for Highly Efficient Human Stem Cell Labeling. Nano Lett, 7:149-154, 2007. (*=Corresponding Author)
5. Huang DM, Hung Y, Ko BS, Hsu SC, Chen WH, Chien CL, Tsai CP, Kuo CT, Kang JC, Yang CS, Mou CY, Chen YC. Highly efficient cellular labeling of mesoporous nanoparticles in human mesenchymal stem cells: implication for stem cell tracking. FASEB J, 19: 2014-2016, 2005.
6. Lin YS, Tsai CP, Huang HY, Kuo CT, Hung Y, Huang DM, Chen YC, Mou CY. Well-ordered mesoporous silica nanoparticles as cell markers. Chemistry of Materials, 17:4570-4573, 2005.