Demeral David Liu, D.D.S., Ph.D.
Joint-appointed Associate Invetigator
Institute of Cellular and Systems Medicine
EDUCATIONPh.D., Mahony Institute of Neuroscience, University of Pennsylvania, USA
M.S., Graduate Institute of Dental Science, National Defense Medical Center, Taiwan
D.D.S., School of Dentistry, National Defense Medical Center, Taiwan
PROFESSIONAL EXPERIENCES- Joint-appointed Associate Investigator, Stem Cell Research Center, National Health Research Institutes, Taiwan (2005 - present)
- Associate Professor and Director, Department of Periodontology and Dentistry, Buddhist Tzu-Chi General Hospital, Taiwan (2005-Present)
- Associate Professor, Institute of Medical Science and Department of Surgery, School of Medicine, Buddhist Tzu-Chi University, Taiwan (2004-Present)
- Clinical Fellow, Department of Periodontology, Tri-Sevice General Hospital, Taiwan (1999-2004)
- Lecturer, Institute of Medical Science and School of Dentistry, National Defense Medical Center, Taiwan (1995-2004)
- Assistant Professor, Department of Pharmacology, National Defense Medical Center, Taiwan (1995-1999)
RESEARCH INTERESTSDr. Liu's Lab investigates the feasibility of autologous cell therapy for neurotrauma and neurodegeneration. Using the stroke and spinal cord injury animal model to perform the preclinical study of human olfactory ensheathing cells-derived from surgical specmens of nasal polyp. Recently, investigating the underlying mechanisms of neuroplasticity for the hidden properties of olfactory ensheathing cells under hypoxic or neurotraumatic stress.
RESEARCH ACTIVITIES & ACCOMPLISHMENTSThe ultimate goal of Dr. Liu's Lab. is to investigate the fesibility of autologous cell therapy for neurotrauma and neurodegeneration. Both stroke and spinal cord injury animal models were used in our Lab. to perform the preclinical study of human olfactory ensheathing cells-derived from surgical specmens of nasal polyp. We are currently investigating the underlying mechanisms of neuroplasticity for the hidden properties of olfactory ensheathing cells under hypoxic or neurotraumatic stress.
SELECTED PUBLICATIONS1.Liu DD, Hsu YH, and Chen HI. The endotoxin-induced lung injury is enhanced in rats with spontaneous hypertension. Journal Clinical Physiology and Pharmacology. 34:61-69, 2007.
2.Shyu WC, Lin SZ, Lee CC, Liu DD, and Li H. Granulocte colony-stimulating factor for acute ischemic stroke: a randomized controlled trial. CMAJ. 174(7):927-33, 2006.
3.Shyu WC, Lin SZ, Liu DD, and Li H. Homing genes, cell therapy and stroke. Frontiers in Bioscience. 11:899-907, 2006.
4.Liu DD, Shyu WC, and Lin SZ. Stem cell therapy in stroke: strategies in basci study and clinical application. Acta Neurochir. 99:1-3, 2006.
5.Chiu CH, Liu DD, Hsu YH, Lee KC, and Chen HI. Propofol exerts protective effects on the acute lung injury induced by endotoxin in rats. Pulmonary Phamacology & Therapeutics. 2006 (accepted).
6.Chung IC, Liu DD, Kao SJ, and Chen HI. N-acetylcysteine attenuates the acute lung injury caused by phorbol myristate acetate in isolated rat lungs. Pulmonary Pharmacology & Therapeutics. (accepted) doi: 10.1016, 2006.
7.Dai NT, Liu DD, Adams EF, Chiang CH, Yen CY, and Coomes AG. A co-culture skin model based on cell support membranes. Biochem Biophys Res Commun. 329:905-8, 2005.