Faculty Profile, National Health Research Institutes, Taiwan

Faculty Profiles

Min-Shi Lee, MPH, Ph.D.

Associate Investigator
Division of Infectious Diseases


  • Ph.D., Centre for the Epidemiology of Infectious Disease, Oxford University, UK, 1999
  • M.P.H., Institute of Public Health, National Taiwan University, Taiwan, 1990
  • B.S., Department of Medical Technology, National Yang-Ming Medical College, Taiwan, 1988


  • Associate Investigator, Vaccine Research and Development Center, National Health Research Institutes, Taiwan (2005-present)
  • Epidemiologist, Scientist, MedImmune Vaccines (formerly Aviron), Mountain View, California, USA (1999-2005)


    Dr. Lees research interests include epidemiology of infectious diseases and vaccine development, especially applying bioinformatics to design of influenza vaccines.


    Dr. Lee is currently working on development of cell-based influenza H5 vaccines and longitudinal epidemiological studies of enterovirus 71 infection. Dr. Lee has authored over 20 original research articles and technology reports. He is a reviewer for several international journals such as Vaccine and Clinical Infectious Diseases, and has organized several internal and national symposia.


  • British Council Scholarship, 1995-1997
  • Dr. K.P. Chens Outstanding Thesis Award. Taiwan Public Health Association, Taiwan, 1995
  • Young Scientist Overseas Travel Award. American Bureau for Medical Advancement in China (ABMAC), Taiwan, 1990


    1.Liao YC*, Lee MS*, Ko CY, Hsiung CA. Bioinformatics models for predicting antigenic variants of influenza A/H3N2 viruses. Bioinformatics. 2008 (in press). (*=joint first authors)

    2.Lee MS*, Chen MC, Liao YC, Hsiung CA. Identifying Potential Immunodominant Amino Acid Positions in Influenza Hemagglutinin and Predicting Antigenic Variants of Influenza A/H3N2 viruses. Vaccine. 25: 8133-9, 2007. (*=corresponding author)

    3.Jin H, Zhou H, Liu H, Chan W, Adhikary L, Mahmood K, Lee MS, Kemble G. Two residues in the hemagglutinin of A/Fujian/411/02-like influenza viruses are responsible for antigenic drift from A/Panama/2007/99. Virology. 336:113-9, 2005.

    4.Greenberg DP, Walker RE, Lee MS*, Reisinger KS, Ward JI, Yogev R, Blatter MM, Yeh SH, Karron RA, Sangli C, Eubank L, Coelingh KL, Cordova JM, August MJ, Mehta HB, Chen W, Mendelman PM. A bovine parainfluenza virus type 3 vaccine is safe and immunogenic in early infancy. J Infect Dis. 191:1116-22, 2005. (*=corresponding author)

    5.Lee MS*, Walker RE, Mendelman PM. Medical burden of respiratory syncytial virus and parainfluenza virus type 3 infection among US children: implications for design of vaccine trials. Human Vaccines. 1:13-18, 2005. (*=corresponding author)

    6.Belshe R, Lee MS, Walker RE, Stoddard J, Mendelman PM. Safety, immunogenicity and efficacy of intranasal, live attenuated influenza vaccine. Expert Rev Vaccines. 3:643-54, 2004.

    7.Lee MS*, Chen JS. Predicting antigenic variants of influenza A/H3N2 viruses. Emerging Infect Dis. 10:1385-90, 2004. (*=corresponding author)