Faculty Profile, National Health Research Institutes, Taiwan

Faculty Profiles

Horng-Yunn Dou, Ph.D.

Assistant Investigator
Division of Infectious Diseases


Ph. D., Microbiology and Immunology, National Yang-Ming University, Taiwan
M.S., Microbiology and Immunology, National Defense Medical College, Taiwan


  • Assistant Investigator, Division of Clinical Research, National Health Research Institutes, Taiwan (2006-present)
  • Assistant Investigator, Vaccine Research and development Center, National Health Research Institutes, Taiwan (2005-2006)
  • Assistant professor, Department of Medical Technology, Taipei Medical University, Taiwan (2002-2005)
  • Postdoctoral research fellow, Division of Mammalian Genetics, Biotechnology Research Institute, National Research Council. Canada (2002-2003)
  • Visiting Scientist, Department of Medicine and Microbiology & Immunology, Albert Einstein Medical College, USA (1999-2000)
  • Chief, Department of Laboratory Medicine, Taipei Municipal Chronic Disease Hospital, Taiwan (1996-2005)


    Dr. Dous major interest is to understand the pathogenesis of tuberculosis and develop vaccine against tuberculosis. Previous of his work was focusing on developing luciferase reporter phage system to detect mycobacterium in clinical specimen. Currently he is working on molecular epidemiology of tuberculosis and the development of rBCG vaccine against Mycobacterium tuberculosis infection.


    Dr. Dou has administrative and management experience, having worked in various capacities in the Taipei Municipal Chronic Disease Hospital for 10 years. During this period he established the standard laboratory procedure for M.TB. He is also the coauthor of the Manuscript for the Tuberculosis Laboratory Diagnosis published by CDC, Taiwan.


    1.Dou HY, Tseng FC, Lu JJ, Jou R, Tsai SF, Chang JR, Lin CW, Miu WC and Su IJ. Stable Association of Mycobacterium tuberculosis Strains with Different Migratory Populations in Taiwan. (submitted)
    2.Bardarov SJr, Dou HY, Jacobs JrWR, Chan J and Riska PF. Detection and drug-susceptibility testing of M.tuberculosis from sputum samples using luciferase reporter phage: comparison with the Mycobacteria Growth Indicator Tube (MGIT) system. Diagnostic Microbiology and Infectious Disease, 45; 53-61, 2003.
    3.Dou HY, Chung KH, Tao HL, Chou JC, Lee HC, Lin BF, Kuo KL, Lo TL, Yip KK and Lin WH. Improve the detection sensitivity of Amplicor (M.tuberculosis test ) for clinical specimen with acid fast negative by a rapid serology test- Biosign kit. J Biomed Lab Sci., 11:43-50, 1999.
    4.Dou HY, Chung KH, Tao HL, Chou JC, Lee HC, Lin BF, Kuo TL and Lin WH. lymphocyte response in human tuberculosis before and after chemotherapy . J Biomed Lab Sci., 11:51-58, 1999.
    5.Dou HY, Chang CM and Hu CP.T cell receptor usage in chronic hepatitis B. J Biomed Sci., 5:428-434, 1998.
    6.Dou HY and Yip KK. Rapid detection of Mycobacterium tuberculosis by DNA amplification and PCR-EIA . J Biomed Lab Sci., 8:44-48, 1996.
    7.Dou HY, Chou JC and Kon Yip KK .The drug resistance tuberculosis in Taipei Municipal hospital, 1991-1994. Thorac Med, 1:101-105, 1996.