Faculty Profile, National Health Research Institutes, Taiwan

Faculty Profiles


Chun-Chen Liao, Ph.D.

Adjunct Investigator
Institute of Biotechnology and Pharmaceutical Research
ccliao@mx-nthu.edu.tw

EDUCATION

  • Ph.D., University of Western Ontario, Canada, 1972
  • B.S., Chemistry, National Taiwan University, Taiwan, 1965

    PROFESSIONAL EXPERIENCES

  • Adjunct Investigator, Division of Certain Research, National Health Research Institutes, Taiwan (2005-present)
  • President, the Chinese Chemical Society, Taiwan (1997-1998)
  • Vice-president, the Chinese Chemical Society, Taiwan (1995-1996)
  • Dean, College of Science, National Tsing Hua University (1992-1998)
  • Editor-in-Chief, Journal of the Chinese Chemical Society (1991-1993)
  • Chairman, Department of Chemistry, National Tsing Hua University (1984-1987)
  • Visiting Scientist, Max-Planck-Institute fur Strahlenchemie, Germany (1982-1983)
  • Professor, Department of Chemistry, National Tsing Hua University, Taiwan (1980-present)
  • Associate Professor, Department of Chemistry, National Tsing Hua University (1975-1980)
  • Maitre-assistant, University of Geneva, Switzerland (1974-1975)
  • Research Associate, Ohio State University, USA (1973-1974)
  • Research Associate, University of Sherbrooke, Canada (1972-1973)

    RESEARCH INTERESTS

    The main research areas of Dr. Liao are organic synthesis and photochemistry.

    RESEARCH ACTIVITIES & ACCOMPLISHMENTS

    The major emphases and efforts of Dr. Liaos research group are organic synthesis and organic photochemistry. The studies of photochemisstry include the investigation of the structural effects in the photorearrangements of heteroaromatic-ring-fused barrelenes, the photochemical reactions of bicyclo[2.2.2]octenones, and the synthetic applications of oxa-di-?-methane photorearrangements and intramolecular enone-olefine photocycloadditions. The synthetic studies mainly involve the synthetic applications of masked benzoquinones, including short and efficient entries to stereoselective syntheses of polysubstituted cyclohexanes, highly oxygenated polysubstituted cis-decalins and quinanes. Dr. Liao and his research team are also interested in the total syntheses of natural products including iridoids, terpenoids, alkaloids and biologically active compounds.

    HONORS & AWARDS

  • International Advisory Board, Encyclopedia of Reagents for Organic Synthesis
  • Chinese Chemical Society Service Award, Chinese Chemical Society, 2002
  • Scholar Award in Science, Ministry of Education, Taiwan 2000
  • Sun Yat-Sen Scholar Award, Sun Yat-sen Cultural Foundation, Taiwan, 1999
  • Chinese Chemical Society Academic Award, Chinese Chemical Society, Taiwan, 1999
  • National Science Council Outstanding Research Award, National Science Council, Taiwan, 1998, 2000
  • Chinese Chemical Society Annual Best Article Awards, Chinese Chemical Society, Taiwan, 1991, 1995
  • University Best Teaching Awards, Tsing Hua University, Taiwan, 1983, 1988, 2002
  • Recipient of Alexander von Humboldt Fellowship, Max-Planck-Institute fur Strahlenchemie, Germany, 1982-1983

    SELECTED PUBLICATIONS

    1.Lin KC, Chittimalla SK, Peddinti RK and Liao CC. Efficient Coupling of Allylstannane with Diels-Alder Cycloadducts Derived from4-Bromo-substituted Masked o-Benzoqinones: Synthesis of 5-allyl-oxatricyclo[m.3.1.0]decenones and Undecenones. J. Chin. Chem. Soc. (Taipei) ,51:1037-1042, 2004.
    2.Chen CH, Peddinti RK, Rao NSK and Liao CC. Dual Behavior of Masked o-Benzoquinones in Intermolecular Diels-Alder Reactions with Acyclic Dienes: A Rapid Entry to Polyfunctionalized Bicyclo[2.2.2]oct-5-en-2-ones and cis-Decalins. J. Org. Chem., 69: 5365-5373, 2004.
    3.Lin YS, Chang SY, Yang MS, Rao CP, Peddinti RK, Tsai YF and Liao CC. Diels-Alder Reactions of 4-Triflyloxy-2,6,6-trimethyl-2,4- cyclohexadienone. An Expedient Methodology for the Synthesis of Bicyclo[2.2.2]oct-5-en-2-ones and Bicyclo[2.2.2]octa-5,7-dien-2-ones. J. Org. Chem., 69:447-458, 2004.
    4.Liao CC and Peddinti RK. Photochemistry of Heteroarene-Fused Barrelene. CRC Handbook of Organic Photochemistry and Photobiology, 2nd ed., Horspool WM and Lenci FE; CRC Press: London, Chapter 32, 32-1 32-17, 2004. (an invited review chapter)
    5.Hsu DH and Liao CC. Total Syntheses of Sesterpenic Acids: Refuted ()-Bilosespenes A and B. Org. Lett., 5:4741-4743, 2003.
    6.Lin SY, Hsieh HP, Peddinti RK and Liao CC. Substituent Effects on Di-p-methane ans Aza-di-p-methane Rearrangements of Dibenzo[f,h]quinoxalino-barrelenes. Tetrahedron Lett,. 44: 8761-8764, 2003.
    7.Yang MS, Lu SS, Rao CP, Tsai YF and Liao CC. Photochemistry of Bicyclo[2.2.2]oct-7-ene-2,5-diones and the Corresponding 5-Hydroxyimino and 5-Methylene Derivatives. J. Org. Chem., 68: 6543-6553, 2003.