Faculty Profile, National Health Research Institutes, Taiwan

Faculty Profiles


Chun-Chen Liao, Ph.D.

Adjunct Investigator
Institute of Biotechnology and Pharmaceutical Research
ccliao@mx-nthu.edu.tw

EDUCATION

  • Ph.D., University of Western Ontario, Canada, 1972
  • B.S., Chemistry, National Taiwan University, Taiwan, 1965

    PROFESSIONAL EXPERIENCES

  • Adjunct Investigator, Division of Certain Research, National Health Research Institutes, Taiwan (2005-present)
  • President, the Chinese Chemical Society, Taiwan (1997-1998)
  • Vice-president, the Chinese Chemical Society, Taiwan (1995-1996)
  • Dean, College of Science, National Tsing Hua University (1992-1998)
  • Editor-in-Chief, Journal of the Chinese Chemical Society (1991-1993)
  • Chairman, Department of Chemistry, National Tsing Hua University (1984-1987)
  • Visiting Scientist, Max-Planck-Institute fur Strahlenchemie, Germany (1982-1983)
  • Professor, Department of Chemistry, National Tsing Hua University, Taiwan (1980-present)
  • Associate Professor, Department of Chemistry, National Tsing Hua University (1975-1980)
  • Maitre-assistant, University of Geneva, Switzerland (1974-1975)
  • Research Associate, Ohio State University, USA (1973-1974)
  • Research Associate, University of Sherbrooke, Canada (1972-1973)

    RESEARCH INTERESTS

    The main research areas of Dr. Liao are organic synthesis and photochemistry.

    RESEARCH ACTIVITIES & ACCOMPLISHMENTS

    The major emphases and efforts of Dr. Liao¡¦s research group are organic synthesis and organic photochemistry. The studies of photochemisstry include the investigation of the structural effects in the photorearrangements of heteroaromatic-ring-fused barrelenes, the photochemical reactions of bicyclo[2.2.2]octenones, and the synthetic applications of oxa-di-£k-methane photorearrangements and intramolecular enone-olefine photocycloadditions. The synthetic studies mainly involve the synthetic applications of masked benzoquinones, including short and efficient entries to stereoselective syntheses of polysubstituted cyclohexanes, highly oxygenated polysubstituted cis-decalins and quinanes. Dr. Liao and his research team are also interested in the total syntheses of natural products including iridoids, terpenoids, alkaloids and biologically active compounds.

    HONORS & AWARDS

  • International Advisory Board, Encyclopedia of Reagents for Organic Synthesis
  • Chinese Chemical Society Service Award, Chinese Chemical Society, 2002
  • Scholar Award in Science, Ministry of Education, Taiwan 2000
  • Sun Yat-Sen Scholar Award, Sun Yat-sen Cultural Foundation, Taiwan, 1999
  • Chinese Chemical Society Academic Award, Chinese Chemical Society, Taiwan, 1999
  • National Science Council Outstanding Research Award, National Science Council, Taiwan, 1998, 2000
  • Chinese Chemical Society Annual Best Article Awards, Chinese Chemical Society, Taiwan, 1991, 1995
  • University Best Teaching Awards, Tsing Hua University, Taiwan, 1983, 1988, 2002
  • Recipient of Alexander von Humboldt Fellowship, Max-Planck-Institute fur Strahlenchemie, Germany, 1982-1983

    SELECTED PUBLICATIONS

    1.Lin KC, Chittimalla SK, Peddinti RK and Liao CC. Efficient Coupling of Allylstannane with Diels-Alder Cycloadducts Derived from4-Bromo-substituted Masked o-Benzoqinones: Synthesis of 5-allyl-oxatricyclo[m.3.1.0]decenones and Undecenones. J. Chin. Chem. Soc. (Taipei) ,51:1037-1042, 2004.
    2.Chen CH, Peddinti RK, Rao NSK and Liao CC. Dual Behavior of Masked o-Benzoquinones in Intermolecular Diels-Alder Reactions with Acyclic Dienes: A Rapid Entry to Polyfunctionalized Bicyclo[2.2.2]oct-5-en-2-ones and cis-Decalins. J. Org. Chem., 69: 5365-5373, 2004.
    3.Lin YS, Chang SY, Yang MS, Rao CP, Peddinti RK, Tsai YF and Liao CC. Diels-Alder Reactions of 4-Triflyloxy-2,6,6-trimethyl-2,4- cyclohexadienone. An Expedient Methodology for the Synthesis of Bicyclo[2.2.2]oct-5-en-2-ones and Bicyclo[2.2.2]octa-5,7-dien-2-ones. J. Org. Chem., 69:447-458, 2004.
    4.Liao CC and Peddinti RK. Photochemistry of Heteroarene-Fused Barrelene. CRC Handbook of Organic Photochemistry and Photobiology, 2nd ed., Horspool WM and Lenci FE; CRC Press: London, Chapter 32, 32-1 ¡V 32-17, 2004. (an invited review chapter)
    5.Hsu DH and Liao CC. Total Syntheses of Sesterpenic Acids: Refuted (¡Ó)-Bilosespenes A and B. Org. Lett., 5:4741-4743, 2003.
    6.Lin SY, Hsieh HP, Peddinti RK and Liao CC. Substituent Effects on Di-p-methane ans Aza-di-p-methane Rearrangements of Dibenzo[f,h]quinoxalino-barrelenes. Tetrahedron Lett,. 44: 8761-8764, 2003.
    7.Yang MS, Lu SS, Rao CP, Tsai YF and Liao CC. Photochemistry of Bicyclo[2.2.2]oct-7-ene-2,5-diones and the Corresponding 5-Hydroxyimino and 5-Methylene Derivatives. J. Org. Chem., 68: 6543-6553, 2003.